For the Wenatchee Playrun (Leavenworth to Cashmere), the solo boater can do an easy shuttle with the Chelan County Link Transit bus. Route 22 runs from right outside the Cashmere mini market up to Peshastin, Happy Wave, and Leavenworth. $1 fare. Weekdays - the bus comes by about 35 after the hour. Saturdays - about every 2 hours. Sundays - gotta ride your bike. The bus schedule is online.
I drop my stuff at the put in, lock my boat, paddle (use a retractable ski lock), and gear and then drive down the the takeout. Bus back up to the put in and go.
The Wenatchee Playrun maintains interesting playspots down to ~1000 CFS.